Dear Editor, The pandemic coronavirus disease 2019 (COVID-19) has changed the approach to every patient, imposing strict preventive measures to all health care professions, beyond the management of critical patients and emergency procedures. 1 The generalized hand-cleaning and prolonged wearing of personal protective equipment (PPE) has exponentially increased the problem of adverse skin events, which was already common in health care workers, 2 but becoming particularly relevant during previous severe acute respiratory syndrome (SARS) outbreak. 3 From the very beginning of current COVID-19 outbreak, a Chinese study reported a prevalence of 97% of skin damage related to prevention measures among health workers. 4 Exposure duration appears as the main risk factor for face dermatitis, particularly wearing masks and goggles over 6 hours, while washing the hands more than 10 times a day could increase hands damage risk. We should also consider the additional exposure for measures application out of work. Moreover, the general population is using PPE, sometimes with less compliant devices, homemade because of the shortage of disposables. The advice on frequent hand cleaning is commonly associated with an excessive use of disinfectants, because of the great fear of the infection.